Cinnamic acids and derivatives
Apexbio Technology LLC CURCUMIN 100MG
Curcumin (CAS 458-37-7) is a natural small molecule known to inhibit tyrosinase activity with an IC50 of 47 M It modulates multiple signaling pathways involved in tumorigenesis and inflammation influencing transcription factors growth factors cytokines receptors and enzymes Clinical trials at Phase I reported no observed toxicity at doses up to 12 g/day however oral bioavailability is limited ( 1% in Phase I/II studies) Additionally curcumin demonstrates potential for Alzheimer s research as evidenced by reducing beta-amyloid (A 40 A 42) production via downregulating presenilin-1 and GSK-3 in SH-SY5Y neuroblastoma cells
eMolecules 2-(4'-Fluorobenzyloxy)phenylboronic acid | 870779-01-4 | 1G | Purity: 98%
Combi-Blocks | 2-(4'-Fluorobenzyloxy)phenylboronic acid | 1G | 870779-01-4 | MFCD07369749
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Apexbio Technology LLC Tyrphostin AG 1296 146535-11-7 10mM (in 1mL DMSO)
Tyrphostin AG 1296 (CAS 146535-11-7) is a selective inhibitor of platelet-derived growth factor receptor (PDGFR) kinase via ATP-competitive binding Its inhibitory activity (IC50 0 3 0 5 M) results from inducing conformational changes in the ATP-binding domain of PDGFR blocking receptor autophosphorylation induced by ligand binding In vitro studies demonstrate inhibition of PDGF-stimulated mitogenesis (IC50 1 5 M) and cell proliferation (IC50 3 2 M) using Swiss 3T3 cells without significant effects on EGF receptor signaling at concentrations up to 100 M Tyrphostin AG 1296 serves as a research tool for investigating PDGFR-mediated signaling pathways
Matrix Scientific 4-CHLOROCINNAMIC ACID-25G
4-Chlorocinnamic acid, 99%; 25g,C9H7ClO2, MFCD00004396, mw 182.61, [1615-02-7]
Matrix Scientific 4-FLUOROCINNAMIC ACID-25G
4-Fluorocinnamic acid, 98%; 25g,C9H7FO2, MFCD00004395, mw 166.15, [459-32-5]
Sigma Organic Chemistry alpha-Fluorocinnamic acid | 1G | 350-90-3 | MFCD00004222
CAS #: 350-90-3
MDL #: MFCD00004222
Purity: >98 %
UNSPSC Code: 12352100
Molecular Weight: 166.15
Sigma Organic Chemistry 4- 4-Fluorobenzyloxy | 1G | MFCD00173651
4-(4-Fluorobenzyloxy)acetophenone, 1G
About This Item:
Linear Formula: C15H13FO2
MDL Number: MFCD00173651
UNSPSC Code: 12352200
Apexbio Technology LLC Ozagrel,10mg CAS# 82571-53-7
Ozagrel is a potent and selective thromboxane A2 synthetase inhibitor with an IC50 of 4 nM. Other sizes are also available. Please inqury us for quote.
eMolecules 5-Bromo-2-methoxycinnamic acid | 40803-53-0 | MFCD00017596 | 1g
Oakwood Chemical | 5-Bromo-2-methoxycinnamic acid | 1g | 537672218 | 011098 | | 40803-53-0 | MFCD00017596 | 257.083 | C10H9BrO3
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eMolecules 2'-(4-Fluorobenzyloxy)acetophenone | 400878-24-2 | MFCD03001269 | 1g
Oakwood Chemical | 2'-(4-Fluorobenzyloxy)acetophenone | 1g | 537671485 | 010106 | | 400878-24-2 | MFCD03001269 | 244.265 | C15H13FO2
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eMolecules 4'-(3-Fluorobenzyloxy)acetophenone | 93291-55-5 | MFCD06411642 | 5g
Oakwood Chemical | 4'-(3-Fluorobenzyloxy)acetophenone | 5g | 537680027 | 022128 | | 93291-55-5 | MFCD06411642 | 244.265 | C15H13FO2
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eMolecules 3-(3-Fluorobenzyloxy)-bromobenzene | 845866-57-1 | MFCD06411668 | 1g
Oakwood Chemical | 3-(3-Fluorobenzyloxy)-bromobenzene | 1g | 537680776 | 023284 | | 845866-57-1 | MFCD06411668 | 281.124 | C13H10BrFO
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eMolecules 3,4-Dichlorocinnamic Acid | 1202-39-7 | MFCD00004385 | 25g
Ambeed | 3,4-Dichlorocinnamic Acid | 25g | 600843378 | A574837 | | 1202-39-7 | MFCD00004385 | 217.050 | C9H6Cl2O2
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