Cinnamic acids and derivatives
Medchemexpress LLC trans-Cinnamic acid | 140-10-3 | 148.16 | 1 G
Trans-Cinnamic acid is a natural antimicrobial with a minimal inhibitory concentration (MIC) of 250 μg/mL against the fish pathogen A. sobria, SY-AS1. It shows moderate inhibition on rainbow trout intestinal isolates A. sobria SY-AS3 and S. baltica, SY-S145, gill isolate F. spartansii SY-FS1, and fish pathogens A. salmonicida ATCC 33658, Listonella anguillarum, SY-L24, V. crassostreae SY-VC10, and Y. ruckeri E42. This acid is more effective on bacteria when the pH of the culture media is not neutralized. It also inhibits M-CSF/RANKL-induced osteoclast differentiation in C57BL/6 mouse bone marrow macrophage with an IC50 > 100 μM.
- Natural antimicrobial
- Effective against various fish pathogens and nonpathogenic isolates
- More effective on bacteria in non-neutralized pH culture media
- Inhibits osteoclast differentiation
Medchemexpress LLC Eleutheroside C (Ethyl α-D-galactoside) | 15486-24-5 | 5 MG
Eleutheroside C, also known as Ethyl α-D-galactoside, is a glycoside isolated from the bulbs of Polianthes tuberosa. This white to off-white solid is intended for research use only.
- Glycoside isolated from Polianthes tuberosa
- 99.90% purity
- Molecular weight: 208.21
- Chemical formula: C8H16O6
- Appearance: Solid
- Color: White to off-white
- Classified as a saccharide
Accela Chembio Inc 4-hydroxy-3 | 5-dimethoxycinnamic Acid | Predominantly Trans | 25g | 530-59-6 | MFCD00004401 | 97+% | Shelf Life: 1080 Days | Light Sensitive
4-hydroxy-3 | 5-dimethoxycinnamic Acid | Predominantly Trans | 25g | 530-59-6 | MFCD00004401 | 97+% | Shelf Life: 1080 Days | Light Sensitive
Medchemexpress LLC Ferulic acid methyl ester (methyl ferulate) | 2309-07-1 | MFCD00017208 | 100.0% | 208.21 g·mol⁻¹ | C11H12O4 | 5 G
Ferulic acid methyl ester is the methyl ester derivative of ferulic acid supplied for research use. It is reported to be cell membrane- and brain-permeable, with antioxidant and anti-inflammatory activity, and has been used to study MAPK signaling and COX-2 expression. The compound is provided at high purity for biochemical and cellular research applications.
- Methyl ester derivative of ferulic acid
- Antioxidant and anti-inflammatory activity
- Cell membrane and brain permeable
- Modulates MAPK signaling and COX-2 expression
- High purity suitable for research applications
Medchemexpress LLC 4-chlorocinnamic acid | 1615-02-7 | MFCD00004396 | 99.0% | 182.61 | C9H7ClO2 | 1mL
4-Chlorocinnamic acid is a derivative of Cinnamic acid (HY-N0610A) 4-Chlorocinnamic acid inhibits the monophenolase and diphenolase activities of mushroom tyrosinase with IC50 values of 0 477 mM and 0 229 mM respectively 4-Chlorocinnamic acid inhibits the mycelial growth of Colletotrichum gloeosporioides 4-Chlorocinnamic acid exhibits anticonvulsant activity against acute epilepsy induced by pentylenetetrazol[1][2][3][4]
Cayman Chemical FerulIc AcId methyl ester 5g
A lipophilic derivative of ferulic acid, demonstrating increased ability to cross cell membranes; at 10-25 UG/ml, inhibits the release of pro-inflammatory cytokines, blocks the expression of COX-2, and reduces NO generation from LPS-stimulated macrophages
Medchemexpress LLC 4-Methoxycinnamic acid | 830-09-1 | 178.19 | 250 G
4-Methoxycinnamic acid | 830-09-1 | 178.19 | 250 G
Medchemexpress LLC p-Coumaric acid-13C3 | 1261170-80-2 | 167.14 | 100 UG
p-Coumaric acid-13C3 is a 13C-labeled version of p-Coumaric acid, an abundant isomer of cinnamic acid known for its antitumor and anti-mutagenic activities. Stable heavy isotopes have been incorporated into this compound, primarily for use as tracers in drug development.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC 2-Propenoic acid,3-(3-hydroxyphenyl)- | 588-30-7 | 100.0% | 164.16 | 100 MG
m-Coumaric acid is a polyphenol metabolite derived from caffeic acid, produced by gut microflora, and its concentration in human biofluids depends on diet. It is a BBB-penetrant metabolite of chlorogenic acid. In vitro, m-Coumaric acid stimulates cerebral nerves and can evoke neurite outgrowth in hippocampal neuronal cells, promoting neuronal differentiation.
- Increases spontaneous locomotor activity in mice
- Inhibits L-dopa oxidation by epidermis tyrosinase
- Attenuates non-catalytic protein glycosylation in retinas of diabetic rats
- Suitable for research and analytical applications
Medchemexpress LLC α-acetamidocinnamic acid | 5469-45-4 | MFCD00188416 | 99.5% | 205.21 | C11H11NO3 | 100 G
α-Acetamidocinnamic acid is a natural-product-derived small molecule used as an analytical standard and research reagent. It has molecular formula C11H11NO3 and molecular weight 205.21 g/mol, and is supplied as an off-white to light yellow solid with high reported purity (99.47%). Batch-specific certificates of analysis and a safety data sheet are available to support quality and safe handling.
Medchemexpress LLC 4-methylcinnamic acid | 1866-39-3 | MFCD00002697 | 99.0% | 162.19 g/mol | C10H10O2 | 1 G
4-Methylcinnamic acid is a cinnamic acid derivative reported to have antifungal activity and is used in research to study antifungal effects and structure-activity relationships among cinnamic acid derivatives. It is a small organic acid (C10H10O2, MW 162.19 g/mol) typically supplied in research pack sizes for in vitro studies.
- Cinnamic acid derivative with reported antifungal activity.
- Suitable for in vitro antifungal and structure-activity studies.
- Chemical formula C10H10O2, molecular weight 162.19 g/mol.
- Predominantly trans isomer reported; high purity (~99%) available.
- Provided in small research pack sizes for laboratory use.
eMolecules 779-89-5 | 3-(Trifluoromethyl)cinnamic acid | Oakwood Chemical | MFCD00004393 | 216.159 | C10H7F3O2 | 97.000 | OC(=O)\C=C\c1cccc(c1)C(F)(F)F | 25g | 537668596
3-(Trifluoromethyl)cinnamic acid | Oakwood Chemical | 779-89-5 | MFCD00004393 | 216.159 | C10H7F3O2 | 97.000 | OC(=O)\C=C\c1cccc(c1)C(F)(F)F | 25g | 537668596
Medchemexpress LLC p-Coumaric Acid Ethyl Ester | 7362-39-2 | 25 MG
p-Coumaric Acid Ethyl Ester is a non-competitive, reversible inhibitor of tyrosinase, utilized in the development of medicines, cosmetics, and fruit preservation products. It boasts a purity of 99.19% and a molecular weight of 192.21, presenting as a light yellow to light brown solid. This compound also exhibits anti-platelet activity.
- Non-competitive, reversible tyrosinase inhibitor
- IC50 of 4.89 μg/mL and Ki of 1.83 μg/mL against tyrosinase
- Quenches intrinsic fluorescence of the enzyme
- Alters L-tyrosine binding affinity through conformational changes in tyrosinase
- Does not bind to the enzyme's copper ion
- Shows anti-platelet activity in rabbit platelet-rich plasma (IC50 = 130.4 μM)
- Soluble in DMSO at 100 mg/mL
Medchemexpress LLC HY-N0610 100mg Medchemexpress, trans-Cinnamic acid CAS:140-10-3 Purity:>98%
Medchemexpress, HY-N0610 100mg trans-Cinnamic acid CAS:140-10-3 trans-Cinnamic acid is a natural antimicrobial, with minimal inhibitory concentration (MIC) of 250 μg/mL against fish pathogen A. sobria, SY-AS1 [1] . Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC 2-Hydroxycinnamic acid | 614-60-8 | HY-W012531 | 99.9% | 164.16 | 25 G
2-Hydroxycinnamic acid is a phenolic acid with antimicrobial and antioxidant properties. It demonstrates antimicrobial activity against *Staphylococcus aureus* without developing resistance, and shows inhibitory effects on HIV/SARS-CoV S pseudovirus infection. Additionally, it exhibits neuroprotective and antitumor activity.
- Possesses antimicrobial and antioxidant properties.
- Exhibits antimicrobial activity against *Staphylococcus aureus*.
- Shows inhibitory effects on HIV/SARS-CoV S pseudovirus infection.
- Has neuroprotective activity.
- Demonstrates antitumor activity.